RESINS(Polystyrene-based)

Name

Structure

Price(US $)

 Descriptin

 Merrifield Resin

1% DVB crosslinked:
100-200 mesh:
* SL ; 0.6-1.4mmol/g
* HL ; 1.4-2.2 mmol/g

Standard support for solid phase synthesis.
Nucleophiles such as amines, carboxylic acids, alcohols and phenols can be coupled to chlorides of Merrifield resins.
Bound material can be released by treatment with HF or TFMSA.

 Wang Resin

1% DVB crosslinked:
100-200 mesh:
* SL ; 0.6-1.4mmol/g
* HL ; 1.4-2.0 mmol/g

The most widely used support for solid phase anchoring acids.
Attachments of carboxylic acids, alcohols and phenols can be accomplished by Mitsunobu coupling or coupling using DIC/DMAP.
Bound material can be released by treatment with 50% TFA/DCM.

 Carboxy Polystyrene Resin

1% DVB crosslinked:
100-200 mesh:
* HL ; 3.0-4.5 mmol/g

  Used for immobilization of amines, alcohols and phenols.
  Immobilization of chemical entities can be carried out using standard coupling reagents.
  These resins can be converted to reactive acid chlorideresins by treatment with thionyl chloride or oxalyl chloride.
  Cleavages are performed through the hydrazinolysis or the reduction with LiBH4.

 2-Chlorotrityl Alcohol Resin

1% DVB crosslinked:
100-200 mesh:
* HL ; 0.6-1.5 mmol/g

 Stable precursor to 2-chlorotrityl chloride resins, can be stored for a long period under room condition.
 To use these resins for solid phase chemistry, these resins should be converted to active chloride resins, which can be achieved with AcOH or treating with SOCl2.

2-Chlorotrityl Chloride Resin

1% DVB crosslinked:
100-200 mesh:
* HL ; 0.6-1.5 mmol/g

 Useful support for solid phase chemistry.
 Almost all nucleophiles including acids, amines, alcohols, phenols, thiols and amides can be anchored to these resins.
 The steric hindrance of trityl linker can prevent the attachment of amino acids from racemization.
  2-chlorotrityl chloride resins are highly acid labile, which enables the cleavage of chemical entities under very mild condition such a treatment with dilute TFA/DCM or AcOH/TFE/DCM.

2-Chlorotrityl Tryptophan Resin

1% DVB crosslinked:

Please inquire

 New polymer support for solid phase peptide synthesis.
 Useful in direct preparation of peptides incepted with tryptophan.

2-Chlorotrityl Amino Acids Resin

1% DVB crosslinked:

Please inquire

 New polymer support for solid phase peptide synthesis.
 Useful in direct preparation of peptides.